COMPARATIVE EFFICACY OF TOBACCO, NEEM OIL ANDIVERMECTIN AGAINST ECTOPARASITE OF GOATS

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2014-12

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Dept. of Pharmacology and Toxicology

Abstract

The experiment was performed to determine the comparative efficacy of neem oil, tobacco, neem oil-tobacco combined and ivermectin against ectoparasites and their effects on certain hematological (TEC, Hb and PCV) parameters in goat. Twenty five goats of both sexes and aged upto 12 to 24 months infested with ticks were randomly divided into 5 equal groups (T0, T1, T2, T3 and T4) and each group consisting of 5 goats. Group T0 kept as infested control group. In group T1, goats treated with neem oil with the dose rate at 4 ml topically applied in the affected area of the body once daily for 28 days was 56.25% effective against tick infestation in goats. In group T2, goats treated once daily for 28 days with tobacco leaves with the dose rate at 1% concentration were effective up to 60% only against tick infestation in goats. In group T3, goats treated once daily for 28 days with neem oil-tobacco leaves (spray) combined with the dose rate at 4ml neem oil and 1% tobacco leaves concentration was found to be 68.96% effective against tick infestation in goats. In group T4, the efficacy of ivermectin (200 g/kg, body weight) is 100% against ticks after 7 days of treatment. The efficacy of neem oil (56.25%), tobacco leaves (60%), neem oil-tobacco leaves combined (68.96%) and ivermectin on the basis of disappearing of ticks, ivermectin was found to be the best drug and was effective within 7 days of post treatment. On the other hand, other drugs showed comparatively less efficacy against tick infestation within 7 days of post treatment. TEC (%) and Hb (%) and PCV (%) level increased (p<0.01) at 21 st and 28 th days of post treatment. From this experiment, it may be suggested that neem, tobacco and both combined may be used as ectoparasiticide instead of ivermectin.

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TOBACCO, , NEEM OIL ANDIVERMECTIN, ECTOPARASITE OF GOATS

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