STUDY ON PREVALENCE AND EFFICACY OF ANTIBIOTICS AGAINST SECONDARY BACTERIAL INFECTION OF FOOT AND MOUTH DISEASE IN CATTLE IN KURIGRAM DISTRICT

Abstract

The study was carried out to investigate the prevalence and efficacy of commercial antibiotics against FMD virus in cattle in the chars of Kurigram district over a period of six months from October, 2014 to March, 2015. A total of 472 animals were monitored randomly on the basis of age, sex, breed and season. More or less similar affected rate was recorded both in male 12.68% and female 12.73% cattle. There was no statistically significant difference in affected rate of FMD in indigenous cattle by age and sex. The affected rate in animal of different age groups ranged from 16.67% in cattle up to 12 months age, 13.33 % in 13 to 26 months, 12.83% in 27 to 45 months, 12.22% in 46 to 60 months age groups in cattle. The affected rate of FMD increased gradually from 7.69 % in October to 9.72% in November to 16% in December with a peak of 18.88 % in January and then gradually decreased to 15.00% in February to 7.78% in March. The affected rate on the basis of breed indigenous animals were 12.30% and the cross breed animals were 13%. Some commercial antibacterial drugs were used to evaluate their efficacy against secondary bacterial infection in the Foot-and-mouth disease affected cattle. Efficacy of commercial antibiotic treatment was observed in four groups of animals. The Amoxicillin for group A, combined Penicillin + Streptomycin for group B, Oxytetracycline for group C, and soda, potassium permanganate, sohaga and honey for group D. Efficacy results of these antibacterial drugs were compared among the treatment groups on the basis of complete recovery from clinical sings and healing of foot lesions in days required. It was observed the efficacy of antibiotic above the mentioned treated group treated with the antibiotic Amoxicillin in group A showed statistically significant result to recover the Foot and Mouth Disease than the other group B, C and D.