Determination of photolytic degradation of Frenxit (Flupentixol- Melitracen)

Abstract

Photodegradation of the product can be easily and precisely describe by measuring the potency of the product. The purpose of the study was to determine the photo degradation of Flupentixol and Melitracen combine tablet. Flupentixol and Melitracen is a combination antipsychotic and antidepressation drug. The photo degradation of flupentixol and Melitracen was determined by the UV spectrophotometer by measuring the absorbance of the compound. Beside the absorbance determination the changes in the physical parameters were also measured for the determination.The sunlight and normal room temperature sample showed a good and impressive result of photodegradation of the compound according to the temperature and duration. Bulb light exposure also showed the degradation but in a same manner. Flupentixol and melitracen are photosensitive drug and espousing it to the light and radiation may hamper the content uniformity of the tablet of compound.