TRANQUILIZING EFFECTS ON DIFFERENT SPECIES OF ANIMALS BASED ON AGE, DOSE LEVEL, ONSET AND DURATION OF ANESTHESIA

Abstract

The effects of xylazine administration on arterial blood pressure, arterial blood pH, blood gases, rectal temperature, and heart and respiratory rates were recorded in healthy dog, cat, goat, cattle, sheep etc.based on age, dose level, onset, and duration of anesthesia. Xylazine (0.2 mg/kg, i/m) was administered. All baseline measurements were taken before the xylazine administration and were repeated at 5, 15-, 30-, 45-, and 60-min intervals. It was found that heart rate decreased at 15 to 60 min and rectal temperature decreased significantly at 30 to 60 min., but respiratory rate did not change significantly. Mean arterial blood pressure declined significantly at 15 to 60 min after anesthesia. In conclusion, reversal with the antagonist atipamezole is advised whenever serious cardiorespiratory problems arise. Medetomidine sedation also causes vomiting, increased urine production, alterations in uterine and endocrine activity, decreased intestinal motility, and lower intraocular pressure.