BACTERIAL ANALYSIS AND ANTIMICROBIAL DRUG RESISTANCE PATTERN OF PATHOGENS ISOLATED FROM WOUND INFECTION

Abstract

A hospital based cross-sectional study was conducted to ascertain bacteriological analysis and antimicrobial drug resistance pattern of pathogens isolated from wound infection. The study was done in St. Vincent Hospital during the period of July 2016 to June 2017. A total of 66 infected wound samples were collected with different variables (sex and age group) and both Gram-positive and Gram-negative bacterial pathogens were isolated by using standard microbiological techniques. Staphylococcus spp., Pseudomonas spp. and E.coli were the predominant causes of wound infections. The overall prevalence of bacterial pathogens in wound infection out of 66 samples was 63.6% Staphylococcus spp., 21.2% Pseudomonas spp. and 15.2% E.coli respectively. Two types of mixed bacterial infections were found. One was Staphylococcus spp. and Pseudomonas spp. mixed infection with 75% prevalence. Another was Staphylococcus spp. and E.coli. mixed infection with 25% prevalence. For antibiogram study 8 common antibiotics were used for antimicrobial sensitivity test. Gram-positive isolates were more sensitive to Gentamycine , Cefixime and Levofloxacin . On the other hand Gramnegative isolates were more sensitive to Gentamycin and Cefixime. The isolates were highly resistance to Ampicillin , Vancomycin and Erythromycin.