Pharmacological Investigations on Melocanna Baccifera

Abstract

Melocanna baccifera (roxb). ln Brine shrimp lethality bioassay the extract showed strong cytotoxicity where the LCso value of the leave extract was 177.86p9/ml. The neuropharmacological activity was evaluated by using hole cross and open field tests where not significant activity and no exploratory behavior was observed in the leavs extract treated mice as was in mice which were administered reference sedative drug diazepam. The analgesic activity was evaluated using acetic acid induced writhing test at the doses of Sgmg/kg, 100m9/kg and 200m9/kg body weight. The anti-inflammatory activity was measured by using Carrageenan- induced paw oedema.