Study on Cyototoxicity and Antimicrobial of Boerhavia diffusa with Ethyl Acetate Solvent

Abstract

The whole plant or its specific parts (leaves, stem, and roots) are known to have medicinal properties and have a long history of use by indigenous and tribal people in :nJia. The medicinal value of this plant in the treatment of a large number of human ailments is :~lcntioned in Ayurveda, Charaka Samhita, and Sushrita Samhita. It has many ethnobotanical .!ses (the leaves are used as vegetable; the root juice is used to cure asthma, urinary disorders, :eukorrhea, rheumati sm, and enc phalitis), and is medicinally used in the traditional, Ayurvedie system. Besides, th~Plant is reported to posses many pharmacological, clinical, and 3.ntimicrobial properties. Recently, the authors observed potent antiviral efficacy of this plant against phytopathogenic viruses. The antiviral agent isolated from this plant was found to be a gl ycoprotein with a molecular weight of 16- 20 kDa. Administered by foliar spraying in the field, this antiviral agent could protect some economically important crops against natural infection by plant viruses. The purpose of this research is to find out the activity of our research plant Boerhavia dWusa against cytotoxicity and microorganisms.During our research work we did Brine shrimp lethality bioassay to measure the activity of Boerhavia diffusa by using solvent Ethyl acetate and Potassium dichromate as Positive control.ln terms of Antimicrobial test, we used 3 types of microorganisms - Staphylococcus aureus, Shigella dysenteriae and Candido albicans.ln terms of first 2 micrroganisms The Ethyl acetate extract of Boerhavia diffusa showed resistant a tivit and for the last 1 it showed intermediate activity.