Masters of Thesis

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    Violence Against Women and Girls in Relation to Access to Water, Sanitation, and Hygiene Facilities
    (Daffodil International University, 2025-12-23) Saha, Pritum Kumar
    This study investigates the critical nexus between violence against women and girls (VAWG) and access to water, sanitation, and hygiene (WASH) facilities in urban lowincome communities, with a specific focus on Dhaka, Bangladesh. Globally, over 2.2 billion people lack access to safely managed drinking water, disproportionately affecting marginalized urban populations. Women and girls in these settings face heightened risks of gender-based violence due to inadequate WASH infrastructure, such as distant water sources and unsafe sanitation facilities. In Bangladesh, rapid urbanization has exacerbated these challenges, with studies indicating that 85% of women in urban slums experience some form of VAWG, often linked to WASH access. This research addresses the intersection of WASH deficiencies and VAWG, highlighting the role of gender inequalities and socio-economic marginalization in perpetuating vulnerability
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    Phytochemical Screening and Biological Tests of Methanol Extract of Ruellia simplex
    (Daffodil International University, 2024-01-22) Tasnim, Mst. Saima
    The phytochemical composition and possible biological activities of Ruellia simplex, a medicinal herb that has conventional uses, were studied. Plant material was extracted using methanol, and the resultant extract was thoroughly screened for the existence of several secondary metabolites using phytochemical analysis. Alkaloids, flavonoids, Saponin, Glycoside, and tannins were found in the results of the research, indicating the plant’s varied chemical composition. The biochemical properties of the Ruellia simplex methanol extract were then assessed using a battery of in vitro experiments and in-vivo anti-diarrheal, in-vitro thrombolytic activity, in vitro antioxidant & in vivo anthelminthic activity. Ruellia Simplex methanol extract showed adequate thrombolytic effectiveness (69%), according to this investigation. Standard ascorbic acid’s DPPH inhibitory effect displays the IC50 (9.072 μg/ml) as the positive control. The Methanol extract of Ruellia Simplex has a notable DPPH inhibitory effect, with an IC50 of 20.487 μg/ml when compared to standard. The findings of this research emphasize Ruellia simplex’s potential uses in medicine and healthcare by providing significant details on the phytochemical makeup of the plant and its biological activities. The results highlight the significance of looking for novel therapeutic compounds in natural sources and may open the door for future studies
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    A Novel Analytical Method Development of Esomeprazole Pellet
    (Daffodil International University, 2024-01-22) Sarker, Md. Shah Newaj
    Proton pump inhibitors (PPIs), also called gastric medicine, are among the most frequently prescribed medications globally. Medications such as Esomeprazole, Omeprazole, Pantoprazole, and others have nearly become ubiquitous in Bangladesh. Although available in various forms on the market, capsules (pellets) are the most prevalent. Analyzing pharmaceuticals is laborious because only a limited number of pharmaceutical companies produce them internally; the rest purchase granules that have been filled into capsule shells and sold. Thus, only a few in-house methods exist to facilitate the analytical process. The majority of them rely on pharmacopoeial methods such as BP and USP. Although these techniques are widely used, they may only apply to some pharmaceuticals. Therefore, this study is preoccupied with developing a novel technique to facilitate the analysis of PPI pellets. It is a finished product for a company that has only sold granules; it is a raw material for a purchaser. The analytical technique can, therefore, be identical for both. For an analyst to analyze these PPI granules, an effective method for both the primary material and the final product must exist. This analysis uses High-Performance Liquid Chromatography (HPLC), the most effective method for separating and identifying mixtures of various components. In addition, distinct reagent and chromatographic conditions are implemented, given that this is a novel methodology. The ultimate findings exhibit encouraging results. This approach reduces both time and analysis costs, albeit with minor drawbacks. Esomeprazole, PPI, particle analysis, HPLC, and the development of analytical methods are all keywords
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    A survey on Knowledge, Attitude, and Practice towards taking Proton Pump Inhibitors (PPIs) among Bangladeshi villagers
    (Daffodil International University, 2024-01-22) Sarker, Mithun
    It is a survey on Knowledge, Attitude, and Practice towards taking Proton Pump Inhibitors (PPIs) among Bangladeshi villagers. Out most of the villagers don’t know about proper use of PPIs. They do not know when it will be taken and why the are taken PPIs? There haven’t any awareness between most of the Bangladeshi villagers. Who don’t have any formal educational knowledge the take PPIs without doctor’s advice. They go to pharmacy and bye PPIs. They don’t know about dose of the PPIs at a time. The take their own advice. They take it after taking food. That’s why it can not work properly. In the result Most of the Bangladeshi villagers are use PPIs. Most of them are woman and who do not have any educational knowledge the use without doctors prescription. Who are Educated they know everything about PPIs. But one part of educated villagers don’t know when it will be take. They take it after taking food. That’s why it can’t work 100% or properly. They do not know about it’s demerits. They don’t have any knowledge it create some adverse effect after taking PPIs. On the other hand who are un educated, don’t have any academic knowledge they don’t have any knowledge about PPIs. They take it without doctor’s prescription. They do not know when it will be taken. And they take it randomly. They also don’t know 30-60 minutes before taking food it will be taken. That’s why there are suffering mane problems and for that reasons PPIs can not work properly. For that reason PPIs don’t it’s 100%.
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    "Phytochemical screening & antistress activities of the methanolic extracts of Melochia Corchorifolia leaves
    (Daffodil International University, 2024-01-01) Bappy, Rakiba Akter
    The present study was undertaken to evaluate the possible “phytochemical screening and antistress activities of the methanol extracts of Melochia Corchorifolia leaves” (family: Sterculiaceae. The leaf's methanol and water extracts have been shown in numerous studies to have antibacterial, antifungal, cytotoxic, and anti-cancer properties. Using conventional procedures, the methanolic extract underwent a phytochemical examination. Numerous phytoconstituents were found, including glycosides, terpenoids, alkaloids, steroids, tannins, phenols, and saponins, according to the analysis. The design research investigates the impacts of spleen anatomy, blood glucose levels, weight fluctuation, and anti stress exercise. The stress group had blood glucose levels of 10.23 ± 1.08 mmol/L and 7.43 ± 0.89 mmol/L, whereas the medicinal sample group had values of 8.9 ± 0.81 mmol/L and 11.03 ± 0.37 mmol/L, respectively. The stress group had a cortisol level of 4.17± 0.19 ug/dl, whereas the medicinal sample group and standard group had levels of 2.13± 0.30 ug/dl and 3.17± 0.18 ug/dl, respectively. Weight fluctuation for the stress group was 26.66 ± 1.20gm, whereas the sample group was 25 ±1 gm. A morphological analysis of the spleen was done in order to evaluate and compare the effectiveness of conventional and herbal medicines against the spleen mass.
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    A survey on “Knowledge, attitude and lifestyle of Nonalcoholic Steatohepatitis (NASH) patients in Chattogram Division”
    (Daffodil International University, 2024-05-14) Hoshen, Muhammad Farhad
    The main causes of nonalcoholic steatohepatitis are known to be excessive food consumption and inactivity (NASH). Currently, the only available treatment for NASH disease is lifestyle modification. It's unclear how best to encourage behavior change in this group of people. This study aimed to characterise the relationship between patient disease knowledge, attitudes, and behaviours as well as evaluate the impact of an educational intervention. There were 171 NASH patient interviews conducted in total, where male patients were 93 and female patients was 78. Though most patients knew that the main therapy was weight loss through diet and exercise, ambiguity surrounding the diagnosis and etiology of their liver disease was a major theme. Male NASH patients' dietary habits were considerably different from those of normal male subjects, including the length of dinnertime, the quantity of rice consumed, and the frequency of consuming meat, fries, Chinese noodles, sweets, and instant food on a weekly basis. There were distinctions in the amount of rice that women ate at suppertime, how often they ate out, and how much they enjoyed sweets. Compared to female patients, male individuals with NASH exercised far less. The lifestyle preferences of NAFL and NASH were remarkably similar. There were no discernible lifestyle differences between NASH individuals who were obese and those who were not. The survey's most surprising conclusion was that men's lifestyles played a significant influence in the emergence of NASH.
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    Dengue Fever: Assessing Awareness, Current Status, and Future Perspectives – A Comprehensive Survey
    (Daffodil International University, 2024-05-14) Rana, Md Sohel
    The study examined dengue fever knowledge and views among 100 adults aged 20-40. This extensive poll evaluated gender, education, age, work, dengue familiarity, and personal history. The research intended to investigate public dengue knowledge and experiences to inform focused public health initiatives. A well-designed survey was given to 100 participants from diverse demographics. The poll included 15 relevant questions on dengue awareness, personal experiences, and treatment. Participants from varied backgrounds completed the online survey, bringing useful insights. 88% of individuals showed acquaintance with dengue, indicating a good overall awareness rate. Majority awareness is a good sign of illness comprehension in the studied community. The research found that 24% of the population had dengue, demonstrating its widespread prevalence. This underscores the need for dengue prevention to reduce public health risks. The study shows a variety of treatments, with paracetamol accounting for 66%. Intravenous fluids (34%), platelet transfusions (14%), and a combination of all therapeutic methods (11%) show the variety of dengue treatments. Individualized therapies for distinct demographic groups are highlighted by these findings. Knowing the incidence and treatment options helps create focused public health interventions. We conclude that this study provides a complete overview of dengue disease views among adults aged 20-40. The report praises general awareness but stresses targeted actions for the 12% who lack understanding. Preventive strategies are crucial given the 24% incidence. The different therapeutic options used emphasize the need for tailored treatments, enabling informed and focused public health programming to reduce dengue fever's effect on the assessed community.
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    Investigating Hemophilia Patients' Experiences and Perceptions of their Health-related well-being in Dhaka City - A Cross-Sectional Study
    (Daffodil International University, 2024-05-06) Munayam, Md.
    Background: Hemophilia, a rare bleeding disorder, presents significant challenges to patients' health-related well-being. Understanding patients' experiences and perceptions is crucial for optimizing their care and improving their quality of life. Methods: A cross-sectional survey was conducted among hemophilia patients in Dhaka City, utilizing structured questionnaires. Results: As per this survey, 41% of responders reported suffering from hemophilia for 1- 5 years. 29% responders have been replied that they have been suffered from hemophilia for 6-10 years. 26% replied that they have been suffered Bleeding of the mouth and gums. 25% responders replied that they have been suffered Bleeding into the joints. 55% retorted that they have been experienced 3-5 times bleeding episode per month. As per this survey most of the responders 60% retorted that their daily activities and mobility has been slightly affected due to bleeding episode. (76%) replied that their family member have been Hemophilia. Conclusion: This study sheds light on the multifaceted challenges faced by hemophilia patients in Dhaka City concerning their health-related well-being. Further research is warranted to explore additional factors influencing patients' experiences and perceptions, with the ultimate goal of developing comprehensive and patient-centered care strategies.
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    Survey on Analyzing Medicine Leaflets in Bangladesh:Impact,Availability,and Public Health Expectations
    (Daffodil International University, 2024-05-06) Shuvo, Shakil Khan
    Background: Bangladesh is one of the South Asian countries having different public health issues like child and maternal death, and outbreaks of communicable – noncommunicable diseases. The desideratum of this research is to investigate and analyze the influence of patient education pamphlets on public health in Bangladesh and to evaluate patient’s expectations, scope of development and provision of current practice of Patient Information Leaflets (PIL). Methods: The study is carried out using an online survey utilizing Google Form and through mass interviews conducted offline. A self-administered questionnaire prepared utilizing a questionnaire-based interview schedule. The entire study was built around a targeted questionnaire that was developed utilizing information from previous research on medicine information leaflets that had been done in various parts of the world as well as some general knowledge about medicine information leaflets. The questionnaire was prepared divided questions in four parts of Personal Information, Knowledge About Medicine Information Leaflet, Usability & Room for Improvement of Medicine Information Leaflet and Health Benefit. Results: Data was collected from 984 people of different ages, genders, demographic locations, education levels and occupation. Among them, 699 people know about it and 340 people read it regularly. Around 41% of people read it to learn about dose but 49% of people find it hard to understand. Although 59% of people admit PIL helps them a lot to understand the medication but 38% thought further improvement is needed. 23% of the population currently use digital media to gain information regarding medicine but 44% of the population prefer it over traditional media as 35% of the population thought digital media helps them to compare between brands. 38% of the population read PIL before buying a medicine but for 28% it influences on their buying decision. Conclusion: Patient Information leaflet makes a great impact on people's understanding of medicine and a more patient oriented leaflet can improve the overall public health scenario in Bangladesh.
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    Hand, Foot, and Mouth Disease: A Questionnaire Survey on Diagnosis, Treatment, and Prevention
    (Daffodil International University, 2024-06-06) Tonny, Yesmin Akter
    Hand, foot, and mouth disease (HFMD) is a viral infection that typically affects children under five years old. It is typified by typical signs including oral herpes and rashes on the hands and feet. This study aims to determine the general public's awareness of hand, foot, and mouth disease (HFMD). An assessment of hand, foot, and mouth illness was created using questionnaires that were distributed one-on-one. According to the survey (31%) responders have been replied that they have idea about Hand, foot, and mouth disease. Most of the participants (69%) have been replied that they have no idea about this illness. 29% participants have been replied that they have been known causes of Hand, foot, and mouth disease. 71% of respondents, or most of them, are unaware of the illness's causes. The majority of respondents (91%) to the study stated that youngsters (ages 5-7) are more vulnerable to hand, foot, and mouth illness. According to 29% of respondents, human contact such as kissing or hugging is how the illness listed earlier is spread. Additionally, 25% and 14% of respondents indicated that they had come into contact with dung and/or touched surfaces or objects, correspondingly. Fruit drinks, citrus fruits, soda, and other acidic foods and beverages can worsen the indications of hand, foot, and mouth disease. 71% of respondents who had family members with hand, foot, and mouth disease said that their doctor had given them a throat swab test to diagnose the condition. For HFMD, there isn't a specific medical intervention. According to 88% of respondents, vitamin D can help reduce hand, foot, and mouth disease discomfort. The majority of respondents (69%), in accordance to the examination, stated that their symptoms persisted for seven days. In summary, it is possible to stop its spread by adhering to the right preventive measures.