Browsing by Author "Islam, MS"

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Comparative study of antihyperglycemic and antihypercholesteromic effect of aquous extract of Allium sativum (Garlic) and Zingiber officinale (Ginger) in alloxan induced rats
(Faculty of Animal Science and Veterinary Medicine, Sher-e-Bangla Agricultural University, Dhaka, Bangladesh, 2016-01) Hossain, MM; Islam, M.; Islam, MS
The aim of this study was to compare the single and combined effect of Allium sativum (Garlic) and Zingiber officinale (Ginger) against hyperglycemia and hypercholsteremia in alloxan induced rats. A total of 300 rats were used for 5 trials. Among them 60 rats (12 normal rats and 48 alloxan induced diabetic rats) were used for each trail. In each trial rats were divided into 5 groups each containing 12 individuals as follows: Group A (Normal Control); Group B (Diabetic control); Group C (Alloxan + Garlic treated); Group D (Alloxan + Ginger treated) and Group E (Alloxan + Garlic + Ginger treated). After 18 hours of starvation, body weights, blood glucose level and blood cholesterol level were measured. Then alloxan were injected @ 100 mg/kg body weight intraperitonially to induce hyperglycemia as well as hypercholsteremia in groups B, C, D, and E. All groups were reared under normal condition from Day 1-10. To ensure the induction of hyperglycemia as well as hypercholsteremia on the day of 10 body weights, blood glucose and cholesterol level were measured. After that all groups were kept for more 21 days. During that period on Day 0, 7, 14, and 21 body weights, blood glucose as well as cholesterol level were measured by using commercially available biochemical kits. Aqueous extract of garlic and ginger were fed @ 500mg and 300mg/kg body weight daily for 21 days in groups C and D respectively and a combined dose (800mg/kg) were used for group E. The blood sugar level and blood cholesterol level were reduced in Group C from 154.5±3.98 to 120.35±4.21 and 209.11±5.24 to 126.66±6.58, respectively. In Group D the blood sugar level and blood cholesterol level were reduced from 155.5±2.99 to 123.12±4.23 and 213.43±6.21 to 128.76±6.98, respectively. But the reduction of blood sugar level and blood cholesterol level were more prominent in Group E from 156±4.11 to 110.21±3.98 and 218.12±6.34 to113.81±6.13, respectively. From the above observations it can be concluded that combined use of garlic and ginger is more effective to control hyperglycemia as well as hypercholsteremia compare to single dose.
Comparative study of antihyperglycemic and antihyperlipidemic activities of aqueous extract of Momordica charantia (bitter gourd) and Coccinia indica (Telakucha) leaves in normal and alloxan diabetic rats
(Faculty of Animal Science and Veterinary Medicine, Sher-e-Bangla Agricultural University, 2022-07) Islam, MS; Sarkar, SK; Hossain, MM; Masum, MA; Rahman, T
ABSTRACT Effective and safer hypoglycemic agents from herbal plants are being considered as area of research as the synthetic oral anti-diabetic agents have several serious adverse effects. The aim of this research was to investigate the single and combined effect of Momordica charantia (bitter gourd) and Coccinia indica (Telakucha) leaves on blood glucose and cholesterol in diabetic rats. In this study 60 rats were divided into 5 groups and containing 12 individuals as follows: normal control (A), diabetic control (B), Alloxan with BG treated (C), Alloxan and TK treated (D) and Group E was Alloxan, BG and TK treated. Alloxan was injected at the dose of 100mg/kg body weight intra-peritoneal to each rat to induce diabetes in groups B, C, D and E. Aqueous extract of BG and TK were fed at a dose of 300mg/kg and 500 mg/kg body weight for 21 days in group C and D, respectively and combined in group E. The body weight, blood cholesterol (mg/dl) and glucose (mg/dl) level were measured on Day 0, 7, 14 and 21. The blood sugar and cholesterol level were reduced in Group C from 178.5±11.55 mg/dl to 120.45±1.98 mg/dl and 209.11±5.24 mg/dl to 126.66±6.58 mg/dl respectively and in group D, they reduced from 150.5±1.6 to 140.17±2.49 mg/dl and 212.43±6.2 to 129.77±5.94 mg/dl respectively. But the reduction of blood sugar level and blood cholesterol level were significant in Group E from 156±4.11 mg/dl to 110.21±3.98 mg/dl and 217.17±4.34 mg/dl to 114.81±4.18 mg/dl, respectively. From these findings it concluded that the combination of BG and TK can be used as anti-hyperglycemic and anti-hypercholesterolemic agent.
Effects of Edible Oils on Biochemical Parameters of Blood in Mice
(Faculty of Animal Science and Veterinary Medicine, Sher-e-Bangla Agricultural University, Dhaka, Bangladesh, 2016-07) Rasel, IH; Ahmad, N; Bhuiyan, MER; Islam, MS
The study was conducted on “Swiss Albino” mice (Mus musculus) fed with additional supplementation of rice bran oil, soybean oil and palm oil to observe their effects on biochemical parameters (total ser um cholesterol, triglycerides, high densi t y lipoproteins and creatinine). A total of 40 (4-5weeks old) mice were randomly divided into 4 equal groups (n=10) as A, B, C and D. Group A was considered as control, fed only commercial ration and other groups were supplemented with rice bran oil (group B), soybean oil (group C) and palm oil (group D) respectively in addition to commercial ration for 60 days. The serum total cholesterol in oil treated groups differed significantly (p<0.05) from control group (95.43 ± 2.16 mg/dl) and was highest in palm oil group (131.468 ± 2.6 mg/dl) among the oil treated groups. The triglycerides in palm oil (172.32 ± 3.09 mg/dl) treated group varied significantly (p<0.05) from control (150.79 ± 3.95 mg/dl) and other oil treated groups. The serum creatinine in palm oil (1.15 ± 0.96 mg/dl) treated group also varied significantly (p<0.05) from control (0.69 ± 0.04 mg/dl) and other oil treated groups. The high density lipoprotein (HDL) in soybean oil treated group (79.48 ± 5.87) differed significantly (p<0.05) from palm oil (63.72 ± 6.81) and control groups (54.47 ± 4.54) but close to rice bran oil group (73.19 ± 3.96). Further investigation is necessary with large number of animals and addition of more parameters like liver function, kidney function which will give more precise information about the effect of these oils.
Establishment of Cost Effective Brooding Method for Chicken
(Faculty of Animal Science and Veterinary Medicine, Sher-e-Bangla Agricultural University, Dhaka, Bangladesh, 2016-07) Islam, MS; Masum, MA; Santa, DH; Alam, MJ; Ali, MM
This study was conducted to compare the effect of different brooding techniques on production performance of broilers. Eighty four numbers of day-old broiler chicks (Cobb 500) were purchased from a local hatchery and were randomly divided into 4 experimental units (with three replicates) of 21 chicks each. Brooding in treatment T1, T2, T3 & T4 were conducted by using Electric heating, Gas, Charcoal and Rice husk; respectively as fuel sources in four separate areas of same specifications. All the experimental birds were provided standard husbandry conditions like light, space, ventilation and relative humidity. The data regarding body weight, feed consumption, feed conversion ratio, and mortality was recorded. At the end of experiment, two birds from each replicate were randomly picked up and slaughtered for determining dressing percentage and necropsy study. Result showed that there was no significant difference (P>0.05) in case of initial body weight, average feed intake, mortality and dressing percentage among different treatment groups. Significantly poorest body weight gain and FCR was observed in rice husk brooding method (P<0.05). Economic study showed that significantly higher performance was observed in electric and gas brooding system with high cost of brooding installation (Tk. 24.42 and 21.26; respectively) as compared to charcoal and rice husk brooding method (Tk. 17.56 and Tk.13.89; respectively) (P<0.05). Based on the productive performance, brooding installation and economic analysis, it can be concluded that charcoal brooder may be a cost effective brooding method which can be applied in chicken farm especially in remote areas where no electricity access or power failure is common.