Phytochemical Investigation of Methanolicextract of Polygonum Lanatum (Fam- Polygonaceae)

Abstract

The objective of this research is to study the phytochemical properties of methanolic extracts of Polygonum lanatum, a plant of Polygonacea family. The phytochemical evaluation was carried out by performing several test TLCs, preparative TLC, & IR test. Polygonum lanatum, a tropical herb, is commonly known as Bishkatali. The plant belongs to family Polygonacea, possessing analgesic, diuretic and anti-inflammatory activity. The plant is distributed in Southeast Asia. Isolation of sterols, terpenoids, flavonoid glycosides, coumaryl glycoside, lignans, quinones, 6-methoxyplumbagin was resulted through the phytochemical investigation on this plant. The leaves are slightly bitter, cure inflammation, skin diseases, laxative, bronchitis, nervous affection, leucoderma, biliousness and good in small pox. The plant possesses nutritional value including-carotene, saponins, cholesterol, glucoside, enhydrin and so on. It is reported that plant possesses Antioxidant, Hepatoprotective, CNS Depressant, Analgesic and Antidiarrheal activity. Thin-layer chromatography (TLC) is a mature and very established technique, frequently used in many fields of applications ranging from natural product analysis to chemical or pharmaceutical applications. Fourier Transform Infrared Spectroscopy (FTIR) identifies chemical bonds in a molecule by producing an infrared absorption spectrum. The spectra produce a profile of the sample, a distinctive molecular fingerprint that can be used to screen and scan samples for many different components. FTIR is an effective analytical instrument for detecting functional groups and characterizing covalent bonding information. TLC & IR test performed to investigate bioactive natural compounds from P. lanatam. Some bands were observed through those tests.