A study on less explored plants with potential neuroprotective activity against neurodegenerative diseases

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2020-12

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BRAC University

Abstract

The gradual deterioration of the structure and function of neurons, including neural death, is known as neurodegeneration. The most known diseases of neurodegeneration are Alzheimer’s, Parkinson's, Huntington's, Amyotrophic sclerosis lateral disease. These diseases are seen throughout the world including Bangladesh and for this reason the demand of neuroprotective agents are high. Now, there are some rare plants such as Ginkgo biloba, Withania somnifera Magnolia officinalis and Hypericum calycimum L. are used not only as folk medicine but also their extracts have shown some crucial effects in lab experiments. Some of the plants such as Centella asiatica, Withania somnifera and Hypericum perforatum L. decreases neural degeneration and also reverses amnesia. Here, this research is going to be discussing on the potential benefits of these plants as neuroprotective agents that are currently unclear or under research.

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Cataloged from PDF version of thesis report.
Includes bibliographical references (pages 48-69).
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020.

Keywords

Neurodegeneration, Amyloid-β, Senile plaque, Amyloid precursor protein, Superoxide dismutase 1

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