Phytochemical Screening, Antioxidant & Antimicrobial Investigations of Methanolic Extract of Bark of Garcinia Cowa

Abstract

The aim of this study was to determine the phytochemical screening , antioxidant activity and antibacterial activity of the methanolic extract of bark of Garcinia cowa. After doing the phytochemical screening , revealed the presence of flavanoid , saponin , steroid and tannin and showed the absence of alkaloids and amtioxidant activity was measured by DPPH scavenging assay having strong DPPH scavenging activity with % inhibition of 84% compared to 92% of standard ascorbic acid in addition to total phenolic content was 411.5333 _+ 19.21805 mg / g gallic acid equivalent. It has also showed strong antibacterial activity against Shigella dysenteriae (zone of inhibition ranged from 15 to 23 mm) and Salmonella paratyphi (zone of inhibition ranged from 13 to 18 mm) and Bacillus sereus (zone of inhibition ranged from 13 to 16 mm) and E. coli (zone of inhibition ranged from 9 to 15 mm) . This study might be helpful to further research to isolate chemical constituents responsible for different medicinal value and drug development.