Key Common Genes of Colorectal Cancer Characteristics Based on Protein-Protein Interactions

Abstract

Background: Bioinformatics handles living organism records and inspects the information using computer science facilities. As a result of improving bioinformatics tools and resources, it is now possible to design the protein-protein interaction (PPI) network from disease-associated common genes. PPI networks are varied based on the interaction scores, p-values and coefficiency. Thus, this paper discovers genetic association among colorectal cancer (CRC) characteristics and identifies the statistically highest key common genes of CRC characteristics based on the PPI networks.