Nanoparticle with microneedle-mediated drug delivery system

Abstract

Microneedle-mediated drug delivery combined with nanoparticles is a promising approach that has garnered significant research interest in recent years. This review discusses the latest advances in this approach, exploring the different types of nanoparticles used, such as liposomes, polymeric nanoparticles, and metallic nanoparticles, and the methods used to incorporate them into microneedles. The potential advantages of using nanoparticles with microneedles, including improved drug bioavailability, targeted drug delivery, sustained release, and reduced side effects, are also discussed. However, the approach faces challenges, such as the need for biocompatible and biodegradable nanoparticles, and optimization of drug loading and release. The review concludes by discussing the future prospects and potential applications of this approach in drug delivery, vaccination, and transdermal sensing. Overall, the combination of nanoparticles with microneedles has significant potential to revolutionize the field of drug delivery and improve patient outcomes by enabling targeted and sustained drug release through a minimally invasive approach.