Study of thrombolytic and anti-arthritic activities of flacourtia jangomas fruit

Abstract

One of the most important medicinal plants is Flacourtia jangomas, often known as Indian plum. It is extensively distributed in South-East Asia and Bangladesh's Chittagong Hill Tracts, Cox's Bazar, and Sylhet area and is used by medical experts to cure a variety of human disorders. Although no research has been done to confirm it, it was thought that F. jangomas fruit also had thrombolytic and anti-arthritic activity. In this in vitro study, methanolic extract of F. jangomas fruit flesh were prepared separately. Later, it was discovered that all extracts had a successful thrombolytic action, with the percentage of clot lysis reaching up to 56.77±7.52% for the Streptokinase(SK) extract and 38.95±4.81% for the MFJ extract of fruit flesh. Additionally, it had an anti-arthritic impact and had a percentage of protein denaturation up to 50.02±3.34%, which was more effective than half of the typical effectiveness of 88.45±4.05%. This made this research successful in terms of both efficacy in F. jangomas.