Study on Effect of Ibuprofen for Remission of Fever in Hospitalized Young Children (age< 4yrs/48 months)

Abstract

Background: Ibuprofen (Propionic Acid derivative) is widely used for treating fever in children. Like Paracetamol , aspirin, and physical methods (such as fanning), Ibuprofen aims to provide relief from symptoms and prevent febrile convulsions. Objectives: To assess the effect of liquid ibuprofen for remission of fever in hospitalized children aged greater than 4 year. Materials and methods: Thirty-two subjects aged less than 1 year admitted to the Institute of Child Health and Shi shu Sasthya Foundation Hospital (ICH&SSF) were included in this study. The body temperature of the patients was recorded at different time interval before and after administration of Ibuprofen preparation. The patients were given 5 to lO-mg/kg dose of liquid Ibuprofen. Body temperature was recorded by thermometer after 15, 30, 60, 90, 120, 150 and 180 minutes of the administration of liquid Ibuprofen. Data analysis: Data were analyzed by using Paired sample T -test. Result: After administration of liquid Ibuprofen the body temperature of the patients -tarts to reduce from 102°F to 99. 12°F. It takes about 2 hours to decrease the body temperature nd after 3 hours the body temperature increases to 99.50F. Conclusion: Liquid preparation of [ ibuprofen has effect of lowering body temperature of the febrile children. : - y words: Ibuprofen, Febrile, convulsions, liquid preparation, T -test.