A survey on Hemoglobin E Trait Prevalence, Clinical Manifestations, and Genetic Considerations at Shaheed Suhrawardy Medical College and Hospital

Abstract

In Southeast Asia and the surrounding regions, hemoglobin E, an abnormality of the human hemoglobin β-chain, is extensively spread. This survey aimed to investigate the prevalence, clinical manifestations, and genetic considerations associated with Hemoglobin E trait among patients at Shaheed Suhrawardy Medical College and Hospital. The examination is led by a questionnaires oriented survey, around 200 populations was being responded for this assessments. As per this survey most of the population 65% retorted that they have been well known about Hemoglobin E trait. (55%) haven’t been experienced symptoms associated with Hemoglobin E trait. 25% responders retorted that they have been felt Jaundice/yellowing of the skin like symptoms. Conferring to that 38% responders retorted Hemoglobin E Trait is an inherited blood disorder. 60% responders retorted that they have been Hemoglobin electrophoresis tested for Hemoglobin E Trait. 30% participants retorted that they have been Genetic tested of the HBB gene for Hemoglobin E Trait. As per this investigation maximum responders (65%) replied that they haven’t been aware of the inheritance pattern of Hemoglobin E Trait. 67% replied that they have been thought genetic counseling is important for individuals with Hemoglobin E Trait. In this investigation most of the responders (92%) replied that their family member have been Hemoglobin E Trait. 95% participants replied that they have been thought Hemoglobin E Trait is not affected daily life activities. Further research is warranted to explore the broader implications of Hemoglobin E trait and to optimize healthcare interventions for affected individuals and their families.