Physicochemical Properties Analysis of Marketed Amitriptyline Hcl Tablets Available in Bangladesh

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dc.contributor.authorBhowmick, Aditi
dc.contributor.authorSaha, Tushar
dc.contributor.authorMondal, Shadhan Kumar
dc.contributor.authorSovon, Md. Shafiqul Islam
dc.contributor.authorKhan, Amran
dc.contributor.authorMasum, Zia Uddin
dc.contributor.authorHossain, Md. Sakhawat
dc.date.accessioned2021-09-21T09:10:50Z
dc.date.available2021-09-21T09:10:50Z
dc.date.issued2019-12-30
dc.description.abstractThe aim of the present investigation was to analyze different physicochemical parameters of marketed Amitriptyline HCI tablets (10mg) available in Bangladesh. Five brands were chosen randomly and purchased from Dhaka city Bangladesh. Diameter, thickness, hardness, friability and disintegration time were performed as per USP monograph and found satisfactory result. In vitro dissolution study was conducted by using apparatus 1 and in 0.1 N HCl media. Four of the five brands successfully met the compendia requirements after 45 minutes where as one brand failed to meet the official monograph. From the investigation it is recommended that pharmacovigilance should be adopted strongly so as to ensure the quality of the product.
dc.identifier.otherhttp://dspace.daffodilvarsity.edu.bd:8080/handle/123456789/6197
dc.identifier.urihttp://dspace.daffodilvarsity.edu.bd:8080/handle/123456789/6197
dc.language.isoen_US
dc.publisherPharmacologyonline
dc.sourceDIU Institutional Repository
dc.subjectAmitriptyline HCl
dc.subjectPhysicochemical properties
dc.titlePhysicochemical Properties Analysis of Marketed Amitriptyline Hcl Tablets Available in Bangladesh
dc.typeArticle

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