Phytochemical and Biological Investigation of the Plants Moringa Oleifera Lam. and Duranta Repens Linn

Abstract

The plant Moringa oleifera Lam. belongs to the family Moringaceae is locally known as "Sajna" (Eng. Drumstick) found to grow every., here in Bangladesh, India, Pakistan and other tropical and subtropical countries. It has various folk medicinal uses and effective against dysentery, diarrhea, cholera, pneumonia, scabies, relieves the pain of gout and acute rheumatism· etc. Isolation of two alkaloids, meringue and Moring nine and an antibacterial substance, pterygospermin have been reported. For chemical investigation, ethanolic extract of the dried powdered root barks of Moringa oleifera Lam. was successively fractionated with petroleum ether (40-60°C) and chloroform. The chloroform soluble fraction was subjected to a column of silica gel, eluted with n-hexane and ethyl acetate and their mixtures and re chromatography of the suitable portion afforded compound-I (31.4 mg) as needles, from petroleum ether, MP. 58-60°C. Compound-I was identified as deoxy-niazimicin (N-benzyl, S-ethyl thiocarbamate), a novel compound by analysis of its spectral data (IR, Mass and NMR) …………………….