An Investigation on Antinociceptive Effect of Abroma Augusta Linn. (Sterculiaceae)
Date
2009-12-21
Authors
Journal Title
Journal ISSN
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Publisher
East West University
Abstract
Abroma augusta Linn (Sterculiaceae), commonly known as Ulatkambal(Bengali). This
plant is used as medicinal plant for its distinct pharmacological activity. Chemical
analysis of this p lant has noticed various chemical properties. The aim of this study was
to investigate the antinociceptive effect of the ethyl acetate extract of A.augusta in acetic
acid-induced writhing test in mice. The result suggests that the extract has exhibited
significant (p<0.05) analgesic effects, which we
'
re comparable with standard drugs. The
bark extracts at 500 and 250 mg/kg showed significant reduction in acetic acid induced
writhing in mice with a maximum effect of65.27% reduction at 500 mg/kg dose.
Description
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.
Keywords
Abroma augusla, ulatkambal, pharmacological activity. writhing test, analgesia