Phytochemical, Anti-Microbial and Cytotoxic Studies on Leaves Extract of Phyllanthus Beillei H

Abstract

Microbial resistant is getting dangerous day by day. To find a new antimicrobial source is very essential. The current research study was designed to assess the antimicrobial activity of methanol extract of Phyllanthus Billie H. by disc diffusion method. By measuring zone of inhibition mild antimicrobial activity of Bacillus subtilis was found and compared with the standard Ciprofloxacin. From the result, it can be concluded that the Phyllanthus beillei H. plant may be a source of antimicrobial constituents. The plant extract also demonstrated promising cytotoxic activity against brine shrimps nauplii. The value of LC50 of methanol extract of Phyllanthus Billie H. was 2.4119 mg/mL which compared with the LC50 value of the standard (0.0171mg/mL). The overall results indicate a strong cytotoxic activity of this plant.