A Study of Analgesic Activity of Methanol and Pet ether Extracts of Barks of Stereospermum Chelonoides

Abstract

The plant Stereospermum chelonoides has been used for the general promotion of health and longevity by Asian tribal. It is used as a traditional medicine for the treatment of various diseases pain, fever, inflammations, asthma, liver disorders etc. The aim of the present study was to evaluate the analgesic activity of pet-ether extract and methanol extract of Stereospermum chelonoides. The powdered barks of Stereospermum chelonoides were extracted with methanol and pet ether. The fraction was used to evaluate analgesic activities. The analgesic activity was measured by acetic acid induced writhing method. Methanol fraction and pet ether fraction showed analgesic activity respectively with 59.53 % inhibition of pain and 55.85% in the P<0.001. The standard (Indomethacin) showed pain of inhibition by 86.96 %. The results of study clearly indicate the presence of analgesic properties of methanol and pet-ether extract. The obtained results provide a support for the use of this plant in traditional medicine and its further investigation.