A review on optogenetics and its potential in neurological disorder management

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Date

2022-10

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BRAC University

Abstract

Neuroscientists have a remarkable capacity to influence neurons because of the latest research technology known as optogenetics. Optogenetics offers significant possibilities as a treatment option for neurological disorders as well as has been acknowledged for a wide range of applications including in cancer treatment, management of cardiovascular disease, treatment of diabetes, gene editing, and regulation of epigenomes. Optogenetics has made significant progress in recent years, supplying us with opsins for possible uses in the management of the neurological disorder. In this technique, the ion channels which are sensitive to light are expressed in neurons, allowing them to be regulated particularly by light. This paper aims to provide an overview of optogenetics, its mechanism, applications, and its advances in the management of neurological disorders.

Description

Cataloged from the PDF version of the thesis.
Includes bibliographical references (pages 53-60).
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.

Keywords

Optogenetics, Neurological disorders, Parkinson, Alzheimer, Epilepsy, Schizophrenia

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