Role of epigenetics in the development of metabolic disorders: a review

Abstract

Metabolic disorders such as diabetes, obesity, cardiovascular diseases and cancer have become a major global health concern accounting for significant morbidity and mortality rates. Although genetic factors largely contribute to these disorders, emerging evidence suggests that epigenetic modifications also play a crucial role in the development and progression of metabolic disorders. This review paper discusses the concept of epigenetics and provides an insight on the role of epigenetics in the development of metabolic disorders.