STUDY ON THE PREVENTION OF ARSENIC TOXICITY IN QUAIL BY USING SPIRULINA AND GARLIC

Abstract

Chronic arsenic (As) toxicity is a severe disease in men and animals which occurs severely in Bangladesh. As contamination in ground water used in drinking is the major concern because arsenic is present in human and animal food chain. This work was done in quails with a view to study the comparative efficacy of Spirulina (Spirulina platensis) and Garlic (Allium sativum) for prevention of arsenic toxicity. Forty quails were used in this study and animals were divided into control group (T0), Arsenic treated group (T1), Arsenic (As) plus Spirulina treated group (T2) and Arsenic (As) plus Garlic treated group (T3). Each group consists of 10 quails. Quails of T0 group were given normal feed and water and kept as control. Quails of T1, T2 and T3 were given 100 mg Arsenic (As) trioxide/L drinking water daily for 30 days. In addition to arsenic (As) trioxide quails of group T2 and T3 were simultaneously fed with Spirulina @ 1 gm/kg feed and T3 were simultaneously feed with Garlic @ 1gm /kg body weight up to 30 days respectively. Five quails from each group (T0, T1, T2 and T3) were sacrificed at 15 days interval in order to determine hematological parameters. Result showed that in group T1, body weight gain was minimum, whereas in groupT2 and T3 the body weight gain in quails were better. Reduction of TEC, Hb values were significant (P<0.01) in T1 group. Whereas in rest groups reduction of TEC, Hb were less than arsenic treated groups. Noticeable change observed in liver and kindey of arsenic (As) treated group in compare to control group in postmortem and histopathological changes. In conclusion, spirulina and garlic have significant effect on body weight, hematological, postmortem and histopathological changes.