Clinical features & outcomes of hospitalized patients with Covid-19 in Dhaka: a single-centered cross-sectional descriptive study

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is still currently a significant public health concern since the outbreak of its pandemic. we aim to share the clinical manifestations of 222 hospitalized COVID-19 patients and their outcomes. This cross-sectional descriptive study is based on clinical records that included patients diagnosed with COVID-19 in Z H Sikder Women’s Medical College & Hospital between December 2020 to August 2021. In total 222 (136 male and 86 female) patients with COVID-19 PCR-positive tests were included in the study. The average age of the study group is 54.81. The most common symptoms were identified as fever (27.2%), cough (22%), sore throat (10.4%), body aches (16.8%), breathlessness (14.5%), diarrhea (2%), and headache (7.1%). Among the patients, 93(41.9%) people needed ICU support during treatment. The most common comorbidities were hypertension (48.3%), chronic kidney disease (8%), diabetes (33.9%), cardiovascular disease (3.8%), and chronic obstructive pulmonary disease (5.9%). The elevated rate had been observed on different biochemical tests such as SGPT [U/L] (mean-45.12), S. Creatinine[mg/dl] (mean-1.5), CRP [mg/l] (mean-84.53), D-dimer [μg/ml] (mean-232.35), S. Ferritin [ng/ml] (mean-502.24). Of 222 patients, 63(28.4%) patients died during treatment and 159(71.6%) were recovered and discharged from the hospital after declaring negative on PCR test for COVID-19. Patients who died typically had preexisting conditions and severe perturbations in inflammatory markers and intensive care requirements.