Marketing Feasibility Study of Ambrisentan

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12/23/2009

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East West University

Abstract

Objective: The purpose of this study to examine the efficacy and safety doses of ambrisentan in patient with pulmonary arterial hypertension. Background: Pulmonary arterial hypertension is a life threatening and progressive diseases with limited treatment option. Endothelin is a vasoconstrictor and smooth muscle cell mitogen (that plays critical role in the pathogens and progression of P AH. Methods: In this regard the writer uses different methods collection of data from different sources. The writer uses books, journal, internet, company visits (RENET A) for IMS data Result: There are five drugs available in the international market for the treatment of P AH. By comprising all the drugs it is found that Ambrisentan is better than all others. Conclusion: Ambrisentan appears to improve exercise capacity, symptom, and hem dynamics in patients with pulmonary arterial hypertension . The incidence and severity of liver enzyme abnormalities appears to low.

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This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.

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Feasibility Study of Ambrisentan

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