ANTIFUNGAL ACTIVITY OF MIXED LIGAND TRANSITION METAL COMPLEXES OF SOME DIBASIC ACID AND HETEROCYCLIC BASES

Abstract

Mixed ligand transition metal complexes of Cu (II), Co (III), Rh (III) and Pt (IV) ions with dibasic acids viz., diphenic acid and adipic acid as primary ligands and amine bases as secondary ligands have been synthesized. Their conventional physical and chemical analyses have been done. The antifungal activities have been evaluated by Disc Diffusion method employed for antifungal assays against two pathogenic fungi. All the complexes show moderate antifungal activity. The highest inhibition of growth occurred on complex [Cu (DA)(8-HQ)] against the fungi Botryodiplodia theobromae and the lowest on complex [Rh (DA)(8-HQ)(H2 O)2] against the fungi Colletotrichum gloesparioides penz.