Browsing by Author "Tagde, Priti"

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    COVID-19 Diagnostic Methods in Developing Countries
    (Daffodil International University, 2022-05-27) Maniruzzaman, Md.; Islam, Md. Missile; Ali, Md. Hazrat; Mukerjee, Nobendu; Maitra, Swastika; Kamal, Mohammad Amjad; Ghosh, Arabinda; Castrosanto, Melvin A.; Alexiou, Athanasios; Ashraf, Ghulam Md.; Tagde, Priti; Rahman, Md. Habibur
    COVID-19 has become one of the few leading causes of death and has evolved into a pandemic that disrupts everyone’s routine, and balanced way of life worldwide, and will continue to do so. To bring an end to this pandemic, scientists had put their all effort into discovering the vaccine for SARS-CoV-2 infection. For their dedication, now, we have a handful of COVID-19 vaccines. Worldwide, millions of people are at risk due to the current pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2). Despite the lack of clinically authorized antiviral medications and vaccines for COVID-19, clinical trials of many recognized antiviral agents, their combination, and vaccine development in patients with confirmed COVID-19 are still ongoing. This discovery gave us a chance to get immune to this disease worldwide and end the pandemic. However, the unexpected capacity of mutation of the SARS-CoV-2 virus makes it difficult, like the recent SAS-CoV-2 Omicron variant. Therefore, there is a great necessity to spread the vaccination programs and prevent the spread of this dreadful epidemic by identifying and isolating afflicted patients. Furthermore, several COVID-19 tests are thought to be expensive, time-consuming, and require the use of adequately qualified persons to be carried out efficiently. In addition, we also conversed about how the various COVID-19 testing methods can be implemented for the first time in a developing country and their cost-effectiveness, accuracy, human resources requirements, and laboratory facilities.
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    The Multifaceted Role of Curcumin in Advanced Nanocurcumin Form in the Treatment and Management of Chronic Disorders
    (Molecules, 2021-11-24) Tagde, Priti; Tagde, Pooja; Islam, Fahadul; Tagde, Sandeep; Shah, Muddaser; Hussain, Zareen Delawar; Rahman, Md. Habibur; Najda, Agnieszka; Alanazi, Ibtesam S.; Germoush, Mousa O.; Mohamed, Hanan R. H.; Algandaby, Mardi M.; Nasrullah, Mohammed Z.; Kot, Natalia; Abdel-Daim, Mohamed M.
    Curcumin is the primary polyphenol in turmeric’s curcuminoid class. It has a wide range of therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic, hepatoprotective, antibacterial, and anticancer effects against various cancers, but has poor solubility and low bioavailability. Objective: To improve curcumin’s bioavailability, plasma concentration, and cellular permeability processes. The nanocurcumin approach over curcumin has been proven appropriate for encapsulating or loading curcumin (nanocurcumin) to increase its therapeutic potential. Conclusion: Though incorporating curcumin into nanocurcumin form may be a viable method for overcoming its intrinsic limitations, and there are reasonable concerns regarding its toxicological safety once it enters biological pathways. This review article mainly highlights the therapeutic benefits of nanocurcumin over curcumin.