Browsing by Author "Syed Rashedul Islam"

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Fabrication of nanoparticle-reinforced composite hydrogel for improved durability, antifouling, and thrombosis-resistance in arteriovenous grafts.
(Colloids and Surfaces B: Biointerfaces, 2025-04-29) Dawit H; Mehmood S; Zahid Hussain; Syed Rashedul Islam; Zhili Wang; Yi Cao; Xingzhu Liu; Renjun Pei
Arteriovenous grafts are routinely designed to provide a deliberate connection between an artery and vein in patients during hemodialysis. The commonly used grafts present significant drawbacks such as thrombosis, bacterial infection, and biofouling which prevents their functionality. To endow hydrogels with improved anti-thrombosis, stable antifouling, and strong mechanical strength, a surface-modified nanoparticle-reinforced nanohybrid hydrogel is developed. In brief, zwitterionic sulfobetaine methacrylate (SBMA) is coated on bentonite clay (BC) nanoparticles via a simple method. BC-SBMA nanoparticles were then loaded onto sodium alginate /polyvinyl alcohol hydrogel composite. Calcium chloride (Ca2+) crosslinking is employed to form stable network and optimize polyvinyl alcohol/sodium alginate (PS) hydrogel composite. BC-SBMA particles were dispersed into PS hydrogel and crosslinked to form nanohybrid hydrogel (PS@BC-SBMA). The nanohybrid hydrogel was characterized for its morphological, mechanical, physicochemical, antibacterial, biocompatibility, antifouling, ex-vivo anti-thrombogenic, and in-vivo anti-inflammatory properties. The results revealed that the presence ofBC-SBMA particles boosted the mechanical strength and facilitated biocompatibility. The presence of zwitterionic polymers provided excellent antifouling properties toward blood platelets, unnecessary proteins, and bacterial strains. Hence, the cooperative effects of the nanohybrid hydrogel such as biocompatibility, antifouling, and mechanical properties lead to a desirable candidate for blood-contacting implants.
PEGylated and peptide-functionalized supramolecular metal-phenolic network coatings for enhanced performance of cardiovascular grafts.
(Chemical Engineering Journal, 2025-07-21) Hewan Dawi; Zahid Hussain; Shah Mehmood; Syed Rashedul Islam; Zhili Wang; Yi Cao; Xingzhu Liu; Wajiha Ahmed; Zixun Wang; Renjun Pei
Cardiovascular devices like catheters, stents, heart valves, and vascular grafts are essential in medical treatments but often cause adverse biological responses, including blood clotting, smooth muscle cell growth, poor re-endothelialization, and inflammation. To address these challenges, a ferric ion and tannic acid (FT) based metal-phenolic network coating was optimized through PEGylation and peptide conjugation for application on blood-contacting substrates. A catechol-conjugated 4-arm poly(ethylene glycol) [P-NHcat]4 was synthesized and incorporated into the FT coating (FT-[P-NHcat]4) using layer-by-layer dip coating techniques to improve its biomedical potential. The surface of the supramolecular coating was further functionalized with YIGSR peptide to promote selective endothelial cell adhesion. Chemical, spectroscopic, structural, and colorimetric analyses confirmed the successful synthesis of [P-NHcat]4 and the uniform, stable application of FT-[P-NHcat]4 coating on a substrate surface. In vitro and ex vivo vascular perfusion assays demonstrated that the PEGylated and peptide-functionalized coating exhibited improved hemocompatibility, enhanced resistance to platelet adhesion, protein repulsion, and antibacterial properties, resulting in reduced thrombus formation. In vivo subcutaneous implantation of FT-[P-NHcat]4-coated substrates in Sprague-Dawley (SD) rats demonstrated resistance to protein adsorption, prevention of blood cell adhesion, and reduced inflammation. These combined properties suggest that designed PEGylated and peptide-functionalized supramolecular coating could improve the long-term patency of cardiovascular grafts.
Super-hydrophobic blended needle-punched nonwovens integrated with silica-aerogels for PM2.5 filtration
(Environmental Engineering Research, 2025-09-30) Hanur Meku Yesu; Syed Rashedul Islam; Xueping Zhang; Xiaohong Qin
This study investigated the hydrophobic and PM2.5 filtration properties of blended needle-punched nonwovens with the treatment of silica-aerogel. The treatment was done by padding. The BET, SEM and FTIR studies were used to investigate the influence of silica-aerogel on needle-punched nonwovens such as surface properties and molecular interaction. All the treated samples showed super-hydrophobic properties with water contact angle (WCA) of around 154.2 - 154.79o , filtration efficiency of 99.07 - 99.21%, pressure drop of 72.83 - 79.71 Pa and dust-holding capacity of 3,459,520 - 3,472,060 particles/cm2 . The findings demonstrated that silica-aerogel played a vital role in enhancing the hydrophobicity, filtration efficiency, dust-holding capacity and fabric density of blended needle-punched nonwovens with statistically significant performance (p<0.05). There was no statistically significant difference in pressure drop, air permeability, porosity, and fabric thickness, which indicated that the treated samples could perform without structure loss as compared to the untreated.
Textile based pressure sensors: a review of materials, fabrication, and applications
(Journal of the Textile Institute, 2025-12-25) Md Aptabusjaman; Syed Rashedul Islam
The greatest breakthrough in modern trends is smart textiles. A magnificent development in the field of wearable and touchable electronics, specifically, for the creation of smart or intelligent textiles, the pressure sensor-based smart textile is highly needed. Designing textile-based products is very difficult, with sensitive power, straightforward production, and low cost. Therefore, this review paper has reported the substantial yarn-based triboelectric and pressure-based sensing smart textiles. The integrated spiral stainless steel yarn has been acting as the inner electrode layer, synthetic filament, and polytetrafluoroethylene filament, respectively, as both positive and negative layers are made of the woven construction. Both mechanical stability and sensing capabilities are strong points of this sensing textile. The created device, which is breathable, light, and even dyeable, can be applied to any chosen body portion to measure dynamic human motions. It can also be used to measure and keep tracking of a variety of human movements at conjunction with numerous joints, including the hand, elbow, knee, and underarms. Additionally, the sensing textile can record pulse signals in real-time and reflect the human body’s current state of health. Thus, this analysis offers a cutting-edge and potentially lucrative path for multifunctional pressure sensor textiles, which have numerous uses in smart clothing and individualized healthcare.