Browsing by Author "Prova, Adiba Hasan"

Filter results by typing the first few letters
Now showing 1 - 2 of 2
  • Thumbnail Image
    Item
    Assessment on the microbial status of potable/ drinking water in Dhaka city and the comparative analysis of different regions of the city on antibiotic resistance
    (2022-01) Amin, Rahaf Bint; Nabila, Antara Ridha; Prova, Adiba Hasan; Rashid, Samia; Das, Devopria; Ahmed, Akash; Haque, Fahim Kabir Monjurul
    Dhaka City is home to nearly 22,478,000 people, but accessible drinking water sources are limited. Moreover, the minimal available water sources are polluted, rendering the Dhaka City population victim of water-borne health hazards. The key water source examined in this study is the community water from street food vendors all over Dhaka City, which is consumed by general people on a regular basis. A total of 47 water samples were collected from tea stalls, street food vendors, and roadside restaurants and the samples were processed within 2 hours of collection. A combination of spread, pour and streak plating methods were used on a variety of selective media, such as MAC, XLD, MSA, TCBS, M-FC, etc. Gram staining and an array of biochemical tests were also performed to identify the target organisms. Antibiotic Susceptibility was further performed to examine the level of antibiotic resistance. In this study, Bacillus spp was the most prevalent (28.57%) bacteria isolated from drinking water. E.coli was found to be the highest one (12%) among a myriad of other enteric pathogens. However, a distressing number of fecal coliforms were found in more or less all the samples The isolates showed highest resistance to Penicillin 80.67% followed by Colistin 50.42%, Cefepime 23.52%, Gentamicin 42.01%, Cefuroxime 43.69%, Erythromycin 24.36%. Diseases related to the serious contamination of drinking water in Dhaka city constitute a major burden on human health and can cause a leading risk factor for infectious diseases including cholera, diarrhea, dysentery and typhoid.
  • Thumbnail Image
    Item
    Exploring the association among breast cancer risk factors, biomarker profiles, and tumor stages: a study from Dhaka, Bangladesh
    (BRAC University, 2024-11) Prova, Adiba Hasan; Haque, Munima; Kabir, Mahmuda
    Breast cancer is one of the most common types of cancer worldwide and continues to be a global public health concern. According to GLOBOCAN estimates, 19% of 68.7 million new breast cancer cases were diagnosed in 2022, making it the most prevalent cancer among females in Bangladesh. Breast cancer is a life-threatening disease in females and the leading cause of mortality among women population. This study aimed to identify the potential predisposing factors and to demonstrate different breast cancer types, stages, and associated risk factors for breast cancer among women. A structured questionnaire including demographic and medical history was used to collect data on factors leading to breast cancer. Data from ninety-four breast cancer patients were collected, and statistical analyses were done by SPSS (version 30) for analysis. The study also showed the risk of breast cancer increases with increasing age. Most of the patients were in their menopausal and postmenopausal age. A potential association between having a first child before the age of 20 and increased breast cancer risk was found. Using oral contraceptive pills (OCP) correlated with higher BMI, which increases the risk of developing breast cancer in this study. Higher BMI patients tend to develop more aggressive cancer types in this study. These patients were diagnosed at an advanced stage; in this case, stage 2 is the most prevalent. In addition, triple-negative breast cancer (TNBC) was the most pervasive biomarker across all the breast cancer patients in this study and showed a tendency to appear in individuals with higher BMI. TNBC patients were diagnosed at an advanced stage, which was linked with difficult prognoses and limited treatment options. This analysis also suggests a possible correlation between oral contraceptive pill use and increased prevalence of HER2+ breast cancer. The findings of this study will help to enhance the knowledge of general people in Bangladesh, especially women, which will lead to the prevention and early diagnosis of breast cancer and thus reduce the mortality and prevalence rates.