Browsing by Author "Islam, Mahfuzul"

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Analyzing the Public Sentiment on COVID-19 Vaccination in Social Media
(Daffodil International University, 22-05-16) Rahman, Md. Mominur; Islam, Md. Rezaul; Akash, Shopnil; -Or-Rashid, Md. Harun; Ray, Tanmay Kumar; Rahaman, Md. Saidur; Islam, Mahfuzul; Anika, Fazilatunnesa; Hosain, Md. Kawser; Aovi, Farjana Islam; Hemeg, Hassan A.; Rauf, Abdur; Wilairatana, Polrat
Nanoscale engineering is one of the innovative approaches to heal multitudes of ailments, such as varieties of malignancies, neurological problems, and infectious illnesses. Therapeutics for neurodegenerative diseases (NDs) may be modified in aspect because of their ability to stimulate physiological response while limiting negative consequences by interfacing and activating possible targets. Nanomaterials have been extensively studied and employed for cancerous therapeutic strategies since nanomaterials potentially play a significant role in medical transportation. When compared to conventional drug delivery, nanocarriers drug delivery offers various benefits, such as excellent reliability, bioactivity, improved penetration and retention impact, as well as precise targeting and administering. Upregulation of drug efflux transporters, dysfunctional apoptotic mechanisms, and a hypoxic atmosphere are all elements that lead to cancer treatment sensitivity in humans. It has been possible to target these pathways using nanoparticles and increase the effectiveness of multidrug resistance treatments. As innovative strategies of tumor chemoresistance are uncovered, nanomaterials are being developed to target specific pathways of tumor resilience. Scientists have recently begun investigating the function of nanoparticles in immunotherapy, a field that is becoming increasingly useful in the care of malignancies. Nanoscale therapeutics have been explored in this scientific literature and represent the most current approaches to neurodegenerative illnesses and cancer therapy. In addition, current findings and various biomedical nanomaterials' future promise for tissue regeneration, prospective medication design, and the synthesis of novel delivery approaches have been emphasized.
PREVALENCE OF MULTIDRUG RESISTANT (MDR) FOOD BORNE PATHOGENS IN RAW CHICKEN MEAT IN DHAKA CITY, BANGLAESH: AN INCREASING FOOD SAFETY CONCERN
(Sher-e-Bangia Agricultural University Research System (SAURES), 2017) Islam, Mahfuzul
Stem Cell Transplantation Therapy and Neurological Disorders
(MDPI, 2022-01-17) Rahman, Md. Mominur; Islam, Md. Rezaul; Islam, Mohammad Touhidul; Rashid, Md. Harun-Or-; Islam, Mahfuzul; Abdullah, Sabirin; Uddin, Mohammad Borhan; Das, Sumit; Rahaman, Md. Saidur; Ahmed, Muniruddin; Alhumaydhi, Fahad A.; Emran, Talha Bin; Mohamed, Amany Abdel-Rahman; Faruque, Mohammad Rashed Iqbal; Khandaker, Mayeen Uddin; -Hedeab, Gomaa Mostafa
Neurodegenerative diseases are a global health issue with inadequate therapeutic options and an inability to restore the damaged nervous system. With advances in technology, health scientists continue to identify new approaches to the treatment of neurodegenerative diseases. Lost or injured neurons and glial cells can lead to the development of several neurological diseases, including Parkinson’s disease, stroke, and multiple sclerosis. In recent years, neurons and glial cells have successfully been generated from stem cells in the laboratory utilizing cell culture technologies, fueling efforts to develop stem cell-based transplantation therapies for human patients. When a stem cell divides, each new cell has the potential to either remain a stem cell or differentiate into a germ cell with specialized characteristics, such as muscle cells, red blood cells, or brain cells. Although several obstacles remain before stem cells can be used for clinical applications, including some potential disadvantages that must be overcome, this cellular development represents a potential pathway through which patients may eventually achieve the ability to live more normal lives. In this review, we summarize the stem cell-based therapies that have been explored for various neurological disorders, discuss the potential advantages and drawbacks of these therapies, and examine future directions for this field.
The Impact of Mucormycosis (Black Fungus) on SARS-CoV-2-Infected Patients
(Daffodil International University, 22-08-19) Islam, Md. Rezaul; Rahman, Md. Mominur; Ahasan, Md. Tanjimul; Sarkar, Nadia; Akash, Shopnil; Islam, Mahfuzul; Islam, Fahadul; Aktar, Most. Nazmin; Saeed, Mohd; Harun-Or-Rashid, Md.; Hosain, Md. Kawsar; Rahaman, Md. Saidur; Afroz, Sadia; Bibi, Shabana; Rahman, Md. Habibur; Sweilam, Sherouk Hussein
The emergence of various diseases during the COVID-19 pandemic made health workers more attentive, and one of the new pathogens is the black fungus (mucormycosis). As a result, millions of lives have already been lost. As a result of the mutation, the virus is constantly changing its traits, including the rate of disease transmission, virulence, pathogenesis, and clinical signs. A recent analysis revealed that some COVID-19 patients were also coinfected with a fungal disease called mucormycosis (black fungus). India has already categorized the COVID-19 patient black fungus outbreak as an epidemic. Only a few reports are observed in other countries. The immune system is weakened by COVID-19 medication, rendering it more prone to illnesses like black fungus (mucormycosis). COVID-19, which is caused by a B.1.617 strain of the SARS-CoV-2 virus, has been circulating in India since April 2021. Mucormycosis is a rare fungal infection induced by exposure to a fungus called mucormycete. The most typically implicated genera are Mucor rhyzuprhizopusdia and Cunninghamella. Mucormycosis is also known as zygomycosis. The main causes of infection are soil, dumping sites, ancient building walls, and other sources of infection (reservoir words “mucormycosis” and “zygomycosis” are occasionally interchanged). Zygomycota, on the other hand, has been identified as polyphyletic and is not currently included in fungal classification systems; also, zygomycosis includes Entomophthorales, but mucormycosis does not. This current review will be focused on the etiology and virulence factors of COVID-19/mucormycosis coinfections in COVID-19-associated mucormycosis patients, as well as their prevalence, diagnosis, and treatment.