Browsing by Author "Bhattacharya, Tanima"

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Applications of Phyto-Nanotechnology for the Treatment of Neurodegenerative Disorders
(Daffodil International University, 2022-02-20) Bhattacharya, Tanima; E Soares, Giselle Amanda Borges; Chopra, Hitesh; Rahman, Md. Mominur; Hasan, Ziaul; Swain, Shasank S.; Cavalu, Simona
The strategies involved in the development of therapeutics for neurodegenerative disorders are very complex and challenging due to the existence of the blood-brain barrier (BBB), a closely spaced network of blood vessels and endothelial cells that functions to prevent the entry of unwanted substances in the brain. The emergence and advancement of nanotechnology shows favourable prospects to overcome this phenomenon. Engineered nanoparticles conjugated with drug moieties and imaging agents that have dimensions between 1 and 100 nm could potentially be used to ensure enhanced efficacy, cellular uptake, specific transport, and delivery of specific molecules to the brain, owing to their modified physico-chemical features. The conjugates of nanoparticles and medicinal plants, or their components known as nano phytomedicine, have been gaining significance lately in the development of novel neuro-therapeutics owing to their natural abundance, promising targeted delivery to the brain, and lesser potential to show adverse effects. In the present review, the promising application, and recent trends of combined nanotechnology and phytomedicine for the treatment of neurological disorders (ND) as compared to conventional therapies, have been addressed. Nanotechnology-based efforts performed in bioinformatics for early diagnosis as well as futuristic precision medicine in ND have also been discussed in the context of computational approach.
Current Intellectual Glance Over Nanoparticles in Cancer and Neurodegenerative Research
(Bentham Science Publishers Ltd., 2022-11-21) Bhattacharya, Tanima; Shen, Bairong; Greig, Nigel H.; Kamal, Mohammad Amjad
Nanoparticles are highly fascinating technologically and are fundamentally important particles due to their large surface area in relation to their volume. They provide numerous advantages in their application to the life- and envi- ronmental-sciences consequent to their particle size (1-100 nm), which can be smaller than the size of a virus; thereby allowing them to potentially strongly adhere to surfactant and other biological materials. In this regard, na- noparticles represent promising agents for attaching biological entities to without changing their functions. There are numerous areas across the sciences where these engineered particles could be hugely beneficial; many of them inadequately explored. To aid understand the fuller potential and efficacies of these particles, more research is needed, and the results are brought into the limelight to allow them to be more fully and rapidly applied. Their eval- uation in the areas of anticancer, antimicrobial, antiviral, anti-carcinogenic, sensory agents with newer techniques, and environmental applications encouraged.
Smartphone Addiction among Students and its Harmful Effects on Mental Health, Oxidative Stress, and Neurodegeneration towards Future Modulation of Anti-Addiction Therapies A Comprehensive Survey based on SLR, Research Questions, and Network Visualization Techniques
(Bentham Science Publishers Ltd., 2022-12-13) Akhtar, Faijan; Patel, Parth K.; Heyat, Md Belal Bin; Yousaf, Saba; Baig, Atif Amin; Mohona, Rashenda Aziz; Mutoffar, Muhamad Malik; Bhattacharya, Tanima; Teelhawod, Bibi Nushrina; Li, Jian Ping; Kamal, Mohammad Amjad; Wu, Kaishun
"Background: Addiction is always harmful to the human body. Smartphone addiction also affects students' mental and physical health. Aim: This study aims to determine the research volume conducted on students who are affected by smartphone addiction and design a database. We intended to highlight critical problems for future research. In addition, this paper enterprises a comprehensive and opinion-based image of smartphone-addicted students. Methodology: We used two types of methods, such as systematic literature review and research questions based on the Scopus database to complete this study. We found 27 research articles and 11885 subjects (mean ±SD: 440.19 ± 513.58) using the PRISMA technique in this study. Additionally, we have deeply investigated evidence to retrieve the current understanding of smartphone addiction from physical changes, mental changes, behavioural changes, impact on performance, and significant concepts. Furthermore, the effect of this addiction has been linked to cancers, oxidative stress, and neurodegenerative disorders. Results: This work has also revealed the future direction and research gap on smartphone addiction among students and has also tried to provide goals for upcoming research to be accomplished more significantly and scientifically. Conclusion: This study suggests future analysis towards identifying novel molecules and pathways for the treatment and decreasing the severity of mobile addiction."