Browsing by Author "Azad, A.K"

Now showing 1 - 3 of 3

An Epidemic Model without Immunity
(Daffodil International University, 2014-07-01) Hasan, Md. Nazmul; Azad, A.K
An epidemic is usually a large and short term outbreak of disease. A disease is called endemic if it persists in the population for a long period of time. In this paper we introduce a model for some diseases which have temporary immunity. It means after recovery, there is immunity but it is not permanent. In this disease, the people are divided into Some groups, susceptible, infective, immune and dead people. The spread of an infectious disease involves not only disease factors such as an infectious agent, mode of transmission, latent period, infection period. It is to be noted that we pay attention to people who are born or die because of any reason except for the disease. Then we get the equilibrium point and prove it is unstable.
In-vitro Study of Formulated Paracetamol Plus Caffeine Tablet with Different Brands Available in Bangladesh
(Pharmacologyonline, 2019-08-30) Rahman, Md. Mizanur; Akther, Md. Tuhin; Talukdar, Sara Jaman; Afroz, Tahmina; Azad, A.K
This study aimed to formulate paracetamol with caffeine tablets and comparing them with four local marketed paracetamol with caffeine coated tablets. Different batches numbers selected the samples randomly and the physicochemical experiments were done according to monographs. The tablets were prepared by using wet granulation method. All the coated tablets passed weight variation test as the percentage of weight variation was within USP limits of ± 5% of the average weight. The chemical assay test of all the tablets showed that none had potency less than the required specifications of USP. The in vitro dissolution test results were found within the BP recommended limits for paracetamol 500 mg & caffeine 65mg film coated tablets. The comparative in-vitro study of FP+C with four different brands showed that FP+C has almost comparable characteristics with these brands. This study also proved the physicochemical equivalency of the four different brands. If any one brand is not available in the market then other three brands can be taken in place of that unavailable brand.
Phytochemical Screening and Pharmacological Studies of Methanol Extract of Polyalthia Suberosa Roxb
(Pharmacologyonline, 2019-04-30) Afroz, Tahmina; Hasan, Md. Imran; Kafi, Md. Abdul Lahil; Azad, A.K; Rahman, Md. Mominur; Akter, Aklima; Rahman, Md. Mizanur
The aim of the study was to find out the phytochemical evaluation, antioxidant, cytotoxic and thrombolytic activity from the leaves of the methanolic extract of the plant of Polyalthia suberosa Roxb. Phytochemical analysis of Polyalthia suberosa Roxb displayed the presence of alkaloids, saponins and tannin types of compounds. The anti-oxidative effect was evaluated using DPPH free radical scavenging activity method. The methanolic extract of Polyalthia suberosa Roxb. leaves is found to have antioxidant activity that will be the IC50 value of standard ascorbic acid for DPPH was 1.85 µg/ml and methanol extract of Polyalthia suberosa Roxb was 8.48 µg /ml. The methanol crude extract of Polyalthia suberosa shows moderate cytotoxic activity against the brine shrimp nauplii. The LC50 value of methanol extract was 0.3119 mg/mL compared with the LC50 value of standard (0.0171 mg/mL). Addition of 100 μl SK, a positive control (30,000 IU), to the clots and subsequent incubation for 90 minutes at 37 °C, showed 88.49% lysis of clot. On the other hand, distilled water was treated as negative control which exhibited a negligible percentage of lysis of clot 10.44%. The results indicated that the extract has moderate antioxidant, cytotoxic and thrombolytic activities.