Browsing by Author "Alam, Nur Haque"

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    Adaptive and inflammatory immune responses in patients infected with strains of Vibrio parahaemolyticus.
    (2003) Qadri, Firdausi; Alam, Muhammad Shamsul; Nishibuchi, Mitsuaki; Rahman, Taufiqur; Alam, Nur Haque; Chisti, Jobayer; Kondo, Seiichi; Sugiyama, Junichi; Bhuiyan, Nurul Amin; Mathan, Minnine M.; Sack, David A.; Nair, G. Balakrish
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    Clinical profile, antibiotic susceptibility pattern of bacterial isolates and factors associated with complications in culture‐proven typhoid patients admitted to an urban hospital in Bangladesh
    (Wiley Online Library, 2/12/2018) Khatun, Halima; Islam, Shoeb Bin; Naila, Nurun Nahar; Islam, Syed Aminul; Nahar, Baitun; Alam, Nur Haque; Ahmed, Tahmeed
    Typhoid fever is one of the major causes of morbidity and mortality in typhoid endemic countries like Bangladesh. However, data on the clinical and microbiological profile as well as factors associated with complications of typhoid in Bangladesh are scarce. We intended to characterise the clinical and microbiological profile of culture-proven typhoid fever and to identify factors associated with complications. Methodology: Retrospective analysis of clinical data from 431 patients with culture-confirmed typhoid fever admitted to Dhaka hospital of International Centre for Diarrhoeal Disease Research, Bangladesh, between January 2010 and December 2014. Clinical and microbiological profiles of the patients including age, sex, and duration of illness prior to hospital admission, haematological parameters and the antimicrobial resistance profile of the infecting isolate, duration of hospital stay and defervescence time were examined by logistic regression to identify the factors associated with complications. Result: About one of three patients were children under 5 years, and 21.5% of them were severely malnourished. During hospitalisation, 17.4% patients developed complications; mainly encephalopathy (6.7%), ileus (6.5%) and pneumonia (3.5%). Among culture-positive cases, 28.3% isolates showed multidrug resistant (MDR) and more than 90% of isolates were resistant to nalidixic acid and had intermediate sensitivity to ciprofloxacin. Five isolates were resistant to azithromycin; all isolates were sensitive to cefixime and ceftriaxone. Complication was independently associated with duration of fever before admission (adjusted odds ratio: 0.85; 95% CI: 0.074–0.97; P < 0.05), thrombocytopenia on admission (AOR: 2.84; 95% CI: 01.06–7.57; P < 0.05), duration of hospital stay (AOR: 1.34; 95% CI: 1.15–1.57; P < 0.01) and defervescence time (AOR: 0.83; 95% CI: 0.70–0.99; P < 0.05). Conclusion: The high prevalence of typhoid fever among under-five children and complications among hospitalised patients are matters of concern. Sensitivity of Salmonella Typhi to ceftriaxone and cefixime was better than to other conventional antibiotics. Shorter duration of fever and thrombocytopenia on admission can be considered as early signs of complications. © 2018 John Wiley & Sons Ltd
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    Efficacy of salovum egg powder containing antisectory factor (AF) in the treatment of severe cholera in adult
    (Dhaka: International Centre for Diarrhoeal Diseases Research, Bangladesh; 2003, 2003) Alam, Nur Haque
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    Evaluation of the effect of hypotonic ORS in the treatment of adult cholera
    (1994-10-13) Alam, Nur Haque; Mahalanabis, Dilip; Sarker, S.A.; Bardhan, P.K.
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    Increased levels of inflammatory mediators in children and adults infected with Vibrio cholerae O1 and O139
    (2002) Qadri, Firdausi; Raqib, Rubhana; Ahmed, Firoz; Rahman, Taufiqur; Wenneras, Christine; Das, Swadesh Kumar; Alam, Nur Haque; Mathan, Minnie M.; Svennerholm, Ann-Mari
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    Role of yersinia infection in childhood diarrhoea and pseudo appendicular syndrome in Bangladesh
    (1983-12-07) Elisabeth, Carniel; Butler, Thomas C.; Alam, Nur Haque
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    Side Effects Following Administration of the First Dose of Oxford-AstraZeneca’s Covishield Vaccine in Bangladesh
    (Infectious Disease Reports, 2021-12) Jahan, Nishat; Rahma, Fahad Imtiaz; Saha, Poushali; Ether, Sadia Afruz; Roknuzzaman, ASM; Sarker, Rapty; Kalam, Khondoker Tashya; Haq, Kashfa; Nyeen, Julkar; Himi, Humayra Zaman; Hossain, Md Nazmul; Chowdhury, Mahtab Hossain; Uddin, Mostafa Moin; Alam, Nur Haque
    In response to the raging COVID-19 pandemic, Bangladesh started its vaccine administration in early 2021; however, due to the rapid development and launch of the vaccines in the market, many people had concerns regarding the safety of these vaccines. The purpose of this study was to evaluate the side effects that were experienced by the Bangladeshi residents after receiving the first dose of the Oxford-AstraZeneca's Covishield vaccine (ChAdOx1nCoV-19). The study was conducted using both online and printed questionnaires and the data were analysed using SPSS. The results included the responses of 474 vaccine recipients from March-April 2021. Pain at the site of injection, fever, myalgia, fatigue and headache were the most commonly reported symptoms, and the overall side effects were found to be significantly more prevalent in the younger population (p ≤ 0.05). These findings were consistent with the results indicated by the clinical trial of ChAdOx1nCoV-19. Logistic regression analysis further revealed that compared to people aged 70 years or above, the incidence of reported side effects was significantly higher in people aged 18-30 years (odds ratio (OR) = 8.56), 31-40 years, (OR = 5.05), 41-50 years (OR = 4.08), 51-60 years (OR = 3.77) and 61-70 years (OR = 3.67). In addition, a significantly higher percentage of female participants suffered from post-vaccination side effects compared to males (OR = 1.51). It was concluded that the Covishield vaccine was well-tolerated among people of different age groups. Nevertheless, further long-term follow-up study with a larger sample size is warranted to establish the long-term safety of the COVID-19 vaccine.
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    Sociodemographic and maternal health-related factors associated with mortality among children under three in Bangladesh: an analysis of data from Bangladesh Demographic and Health Survey 2017-18
    (Scopus, 2024-11) Mim, Shanta Akter; Uddin, Md. Fakhar; Haque, Md. Ahshanul; Tariquajjaman, Md.; Jabeen, Ishrat; Latif, Mubassira Binte; Sumi, Asma-Ul-Husna; Aarshe, Fatema; Hossain, Md. Hasibul; Nabi, Sumaiya; Hossain, Md. Alamgir; Khan, Mohammad Niaz Morshed; Saha, Akash; Ahmed, Tahmeed; Alam, Nur Haque; Chisti, Mohammod Jobayer
    Abstract Background Child mortality remains remarkably high in many low- and middle-income countries (LMICs), including Bangladesh. This study aimed to identify the sociodemographic and maternal health-related factors associated with under three (U3) child mortality in Bangladesh. Methods We extracted data of 5299 U3 children from Bangladesh Demographic and Health Survey (BDHS) 2017-18. We used descriptive statistics to summarize the data. The chi-square (χ2) test, simple and multiple Firth logistic regression were performed to test the associations between priori-defined factors and U3 mortality. Results In Bangladesh, the U3 child mortality rate was 35 deaths per 1,000 live births, with a median age at death of less than one month. The adjusted model revealed that the odds of U3 child mortality were higher among children born to mothers aged between 30 and 39 years [adjusted odds ratio (AOR) = 2.01, 95% confidence interval (CI): 1.30–3.11; p-value (p) = 0.002], those who did not use any contraceptive [AOR = 2.57, 95% CI: 1.90–3.47; p < 0.001], with first pregnancy [AOR = 14.91, CI: 4.60–48.30; p < 0.001], had birth interval less than 24 months [AOR = 2.10, CI: 1.23–3.60; p = 0.007], children born to mothers who delivered vaginally [AOR = 3.18, 95% CI: 2.07–4.87; p < 0.001]. However, lower odds of mortality were observed among children of mothers with higher education levels [AOR = 0.50, 95% CI: 0.28–0.90; p = 0.021] and families with more than five members [AOR = 0.61, 95% CI: 0.45–0.83; p < 0.01]. In addition, religion, birth attendant during delivery, and the child’s birth order were significantly associated with U3 child mortality, whereas mortality did not vary significantly across the divisions. Conclusions Higher odds of U3 child mortality were associated with mothers who did not use contraceptives, delivered vaginally, and were aged 30–39 years in Bangladesh. Conversely, higher maternal education and larger family size were associated with lower odds of U3 child mortality. The findings suggest that community-based family planning awareness programs focused on contraceptive use, as it prevents childbirth and is also a marker of health service usage.
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    The adaptive and inflammatory immune responses in patients infected with strains of vibrio parabemolyticus [conference paper]
    (2002) Qadri, Firdausi; Alam, Muhammad Shamsul; Nishibuch, Mitsuaki; Rahman, Taufiqur; Alam, Nur Haque; Chistti, Jobayer; Kondo, Seiichi; Sugiyama, Junichi; Bhuiyan, Nurul Amin; Mathan, Minnie M.; Sack, David A.; Nair, G. Balakrish